abstract：:The distribution and nature of 125I-atrial natriuretic peptide binding sites have been examined in the brain and pituitary gland of the toad, Bufo marinus, using tissue section autoradiography, affinity cross-linking and electrophoresis, guanylyl cyclase assays and molecular analysis of natriuretic peptide receptor C ...

journal_title：Cell and tissue research

authors： McLeod JL,Donald JA

更新日期：2000-10-01 00:00:00

abstract：:To investigate the role of RhoA on the intracellular membrane dynamics of lysosomes in rat hepatoma cells (MM1), we analyzed the localization of lysosomal aspartic proteinase cathepsin D by confocal immunofluorescence microscopy in the dominant active RhoA-transfected cells. Here we show that the transfection of the d...

journal_title：Cell and tissue research

authors： Nishimura Y,Itoh K,Yoshioka K,Uehata M,Himeno M

更新日期：2000-09-01 00:00:00

abstract：:Gravid females of the parasitoid fly species Ormia ochracea (Diptera: Tachinidae) rely on their sense of hearing to detect and localize their hosts, field crickets of the genus Gryllus. As in any hearing insect species, the fly's auditory system consists of a rather complex cascade of mechanical and physiological mech...

journal_title：Cell and tissue research

authors： Robert D,Willi U

更新日期：2000-09-01 00:00:00

abstract：:The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...

journal_title：Cell and tissue research

authors： Hansen GN,Williamson M,Grimmelikhuijzen CJ

更新日期：2000-08-01 00:00:00

abstract：:Cell degeneration, as a phenomenon accompanying developmental processes, was originally described over a century ago. Apoptosis, a term introduced approximately three decades ago, has occupied investigators particularly with respect to cell and tissue kinetics, emphasizing its role in the disposal of supernumerary, ma...

journal_title：Cell and tissue research

authors： Poelmann RE,Molin D,Wisse LJ,Gittenberger-de Groot AC

更新日期：2000-07-01 00:00:00

abstract：:Apoptosis is a form of programmed cell death that occurs in neurons during development of the nervous system and may also be a prominent form of neuronal death in chronic neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Recent findings also implicate apoptosis in neuronal degeneration after is...

journal_title：Cell and tissue research

authors： Mattson MP,Culmsee C,Yu ZF

更新日期：2000-07-01 00:00:00

abstract：:Rats were injected with liposomes containing iodixanol (CTP10 Injection; 100 mg iodine per kg body weight) followed by a second injection of 125I-tyramine-cellobiose-albumin microspheres. The amounts of phagocytosed and degraded labelled albumin in liver were measured. A reduced uptake and degradation of albumin micro...

journal_title：Cell and tissue research

authors： Kindberg GM,Tolleshaug H,Skotland T

更新日期：2000-06-01 00:00:00

abstract：:Drosophila melanogaster photoreceptors are highly polarized cells and their plasma membrane is organized into distinct domains. Zonula adherens junctions separate a smooth peripheral surface, the equivalent of the basolateral surface in other epithelial cells, from the central surface (approximately equal to apical su...

journal_title：Cell and tissue research

authors： Yasuhara JC,Baumann O,Takeyasu K

更新日期：2000-05-01 00:00:00

abstract：:In recent years, data have accumulated suggesting that the role of neurotrophins and Trk receptors may not be limited to the nervous system, and the presence of these substances has been detected in a variety of vertebrate and invertebrate non-nervous tissues. This study was designed to map the expression of immunorea...

journal_title：Cell and tissue research

authors： Hannestad J,Marino F,Germanà A,Catania S,Abbate F,Ciriaco E,Vega JA

更新日期：2000-04-01 00:00:00

abstract：:In mouse hepatocytes, the gap junctional proteins connexin32 (Cx32) and connexin26 (Cx26) are expressed in the same gap junctional plaque. Expression of the major Cx32 protein is downregulated during liver regeneration and cholestasis. Here we have analyzed the acute-phase response (after experimental inflammation) an...

journal_title：Cell and tissue research

authors： Temme A,Ott T,Haberberger T,Traub O,Willecke K

更新日期：2000-04-01 00:00:00

abstract：:Dietary restriction (DR) retards physical growth, resulting in small body size, reduced liver weight and reduced number of hepatocytes in rats. We examined the effects of DR on proliferation and apoptosis of hepatocytes during development and explained these changes subcellularly using immunohistochemistry for bromode...

journal_title：Cell and tissue research

authors： Higami Y,Shimokawa I,Ando K,Tanaka K,Tsuchiya T

更新日期：2000-03-01 00:00:00

abstract：:Although cartilage is considered to be devoid of innervation, axons occur in the perichondrium and during development in cartilage canals, thereby having a relatively close spatial relationship to chondroblasts and chondrocytes. The present study locates the source of the sensory innervation of the femoral cartilagino...

journal_title：Cell and tissue research

authors： Edoff K,Grenegård M,Hildebrand C

更新日期：2000-02-01 00:00:00

abstract：:Gastrin stimulates gastric acid secretion by acting on the cholecystokinin B/gastrin receptor (CCK-BR). The localization of this receptor at the cellular level showed conflicting results in animal studies and has not been described in man by immunohistochemistry. The aim of the present study is to characterize the pre...

journal_title：Cell and tissue research

authors： Kulaksiz H,Arnold R,Göke B,Maronde E,Meyer M,Fahrenholz F,Forssmann WG,Eissele R

更新日期：2000-02-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is the latest member of the vasoactive intestinal polypeptide (VIP) family of neuropeptides present in nerve fibres in many peripheral organs. Using double immunohistochemistry, with VIP as a marker for intrinsic innervation and calcitonin-gene related peptide...

journal_title：Cell and tissue research

authors： Hannibal J,Fahrenkrug J

更新日期：2000-01-01 00:00:00

abstract：:Rhabdomeres of the Drosophila melanogaster canoemisl mutant ommatidia were twisted, branched, and often fused to each other. A considerable proportion of rhabdomeres were found to have fallen below the retinal basement membrane. Electron-microscopic observations of the mutant ommatidia revealed that microvilli, the su...

journal_title：Cell and tissue research

authors： Matsuo T,Takahashi K,Suzuki E,Yamamoto D

更新日期：1999-12-01 00:00:00

abstract：:We used a combined biochemical and histocytochemical approach to study ecto-ATPase in the rat cardiac muscle. The reaction medium employed for histocytochemical detection was optimized in biochemical assays to achieve the highest enzyme activity and lowest inhibition by the capture agent used for visualization of the ...

journal_title：Cell and tissue research

authors： Zinchuk VS,Okada T,Kobayashi T

更新日期：1999-12-01 00:00:00

abstract：:We previously demonstrated that GLUT2, a facilitated-diffusion glucose transporter isoform known to play critical roles in the regulation of systemic blood glucose level, is present at the apical ends of Müller cells in the rat retina. As a means of elucidating the ontogeny and possible role(s) of GLUT2 in the develop...

journal_title：Cell and tissue research

authors： Watanabe T,Nagamatsu S,Matsushima S,Kondo K,Motobu H,Hirosawa K,Mabuchi K,Kirino T,Uchimura H

更新日期：1999-11-01 00:00:00

abstract：:Ultrastructural aspects of hypertrophic chondrocytes in hamster and mouse epiphysial cartilage were examined in relation to their metabolic activities. With the hypertrophic change, cytoplasmic vacuolization proceeded leaving the partially intact endoplasmic reticulum (ER). In the hypertrophic cells, cytoplasmic hyalu...

journal_title：Cell and tissue research

authors： Takada Y,Sakiyama H,Kuriiwa K,Masuda R,Inoue N,Nakagawa K,Itano N,Saito T,Yamada T,Kimata K

更新日期：1999-11-01 00:00:00

abstract：:Nerves containing the calcium-binding protein calretinin have been reported in several organs but not in female reproductive organs and associated ganglia. This study was undertaken to determine if nerves associated with the uterus contain calretinin and the source(s) of calretinin-synthesizing nerves in the rat (are ...

journal_title：Cell and tissue research

authors： Papka RE,Collins J,Copelin T,Wilson K

更新日期：1999-10-01 00:00:00

abstract：:TFF-peptides (formerly P-domain peptides, trefoil factors) are typical secretory products of mucin-producing cells and seem to influence the rheological properties of mucous gels. Here, localization studies of TFF-peptides in human salivary glands are presented. Expression studies (polymerase chain reaction) revealed ...

journal_title：Cell and tissue research

authors： Jagla W,Wiede A,Hinz M,Dietzmann K,Gülicher D,Gerlach KL,Hoffmann W

更新日期：1999-10-01 00:00:00

abstract：:Endothelial repair to reestablish structural integrity following wounding is a complex process. Since the actin cytoskeleton undergoes specific changes in distribution as quiescent endothelial cells switch to activated migrating cells over a 6-h period following wounding (Lee et al. 1996), we studied tyrosine phosphor...

journal_title：Cell and tissue research

authors： Lee TY,Gotlieb AI

更新日期：1999-09-01 00:00:00

abstract：:In this immunocytochemical study we investigated the distribution of nervous structures in the lower lip of adult rats. The region is characterized by a rich cutaneous and mucosal sensory innervation originating from terminal branches of the trigeminal system. Lower lip innervation was investigated by detection of the...

journal_title：Cell and tissue research

authors： Verzé L,Paraninfo A,Ramieri G,Viglietti-Panzica C,Panzica GC

更新日期：1999-08-01 00:00:00

abstract：:We have developed a primary cell culture system of antennal mechanoreceptor neurons from early-stage pupal sphinx moth Manduca sexta. Dissociated neurons from the moth antennae differentiated, grew and survived for several weeks in a conditioned culture medium. Bipolar neurons with soma diameters of 10-25 microns from...

journal_title：Cell and tissue research

authors： Torkkeli PH,French AS

更新日期：1999-08-01 00:00:00

abstract：:Hypothalamic slices containing the lateral hypothalamic area (LHA) were prepared from 6- to 8-day-old rats and maintained in stationary culture for up to 35 days in order to analyse how well the melanin-concentrating hormone (MCH) neurons survived. As previously reported for other brain areas, this method yielded a lo...

journal_title：Cell and tissue research

authors： Bayer L,Jacquemard C,Fellmann D,Griffond B

更新日期：1999-07-01 00:00:00

abstract：:Endothelial cells separate the intra- and extravascular space and regulate transport processes between these compartments. Since intercellular junctions are required for these specific cell functions, the cell-cell contacts in the permanent cell line ECV304 were systematically analyzed and compared with human umbilica...

journal_title：Cell and tissue research

authors： Kiessling F,Kartenbeck J,Haller C

更新日期：1999-07-01 00:00:00

abstract：:The objectives of these studies were to determine if (1) hypertrophy-stimulated myogenic regulatory factor (MRF) mRNA increases occur in the absence of proliferating satellite cells, and (2) acute hypertrophy occurs without satellite cell proliferation. Adult and aged quails were exposed to 0 or 2500 Rads gamma irradi...

journal_title：Cell and tissue research

authors： Lowe DA,Alway SE

更新日期：1999-06-01 00:00:00

abstract：:The accessory medulla with its associated pigment-dispersing hormone-immunoreactive neurons appears to be the pacemaker that controls the circadian locomotor activity rhythm of the cockroach Leucophaea maderae. To permit studies at the level of individual, identified, pacemaker neurons, we developed specific long-term...

journal_title：Cell and tissue research

authors： Petri B,Stengl M

更新日期：1999-06-01 00:00:00

abstract：:The functional expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1) and MAdCAM-1 in the choroid plexus is indicative of a role of this structure in the communication of the immune system with the central nervous system (CNS). In order to gain further insight into the pos...

journal_title：Cell and tissue research

authors： Wolburg K,Gerhardt H,Schulz M,Wolburg H,Engelhardt B

更新日期：1999-05-01 00:00:00

abstract：:Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...

journal_title：Cell and tissue research

authors： van Wezel IL,Irving-Rodgers HF,Sado Y,Ninomiya Y,Rodgers RJ

更新日期：1999-05-01 00:00:00

abstract：:The vertebrate limb is a powerful model system for studying the cellular and molecular interactions that determine morphological pattern during embryonic development. Recent advances in our understanding of these interactions have shed new light on the molecular mechanisms of vertebrate limb development, evolution and...

journal_title：Cell and tissue research

authors： Cohn MJ,Bright PE

更新日期：1999-04-01 00:00:00

abstract：:Recent evidence indicates that many molecules involved in generating and patterning the limbs also play a role during craniofacial morphogenesis. On the surface, this is an unexpected finding given that these regions of the body have separate evolutionary origins, are composed of different embryonic tissues, and are q...

journal_title：Cell and tissue research

authors： Schneider RA,Hu D,Helms JA

更新日期：1999-04-01 00:00:00

abstract：:The skeletal body muscle of vertebrates is derived from segmentally arranged mesodermal structures, the somites. Only the dorsal epithelial half of the somite, the dermomyotome, gives rise to muscle cells during normal development. Head muscle takes its origin from the somites, the unsegmented paraxial head mesoderm a...

journal_title：Cell and tissue research

authors： Brand-Saberi B,Christ B

更新日期：1999-04-01 00:00:00

abstract：:NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...

journal_title：Cell and tissue research

authors： Martone ME,Edelmann VM,Ellisman MH,Nef P

更新日期：1999-03-01 00:00:00

abstract：:Voltage-gated Na+ channels are expressed by highly metastatic MAT-LyLu cells, but not by poorly metastatic AT-2 cells, derived from the rodent Dunning model of prostatic cancer. We have investigated the possible involvement of these channels in the morphological development of the cells. Incubation of both the MAT-LyL...

journal_title：Cell and tissue research

authors： Fraser SP,Ding Y,Liu A,Foster CS,Djamgoz MB

更新日期：1999-03-01 00:00:00

abstract：:The relationship between nitric oxide synthase (NOS)- and galanin-immunoreactive nerve terminals and the origin of NOS-immunoreactive nerve terminals on the motor endplates in the striated muscles of the rat esophagus was investigated. Double immunohistochemical staining revealed a dual innervation of motor endplates ...

journal_title：Cell and tissue research

authors： Kuramoto H,Kawano H,Sakamoto H,Furness JB

更新日期：1999-02-01 00:00:00

abstract：:By using an antiserum raised against a crustacean beta-pigment-dispersing hormone (PDH), the distribution and chemical neuroanatomy of PDH-like immunoreactive neurons was investigated in the central nervous system of the gastropod snails, Helix pomatia and Lymnaea stagnalis. The number of immunoreactive cells in the H...

journal_title：Cell and tissue research

authors： Elekes K,Nässel DR

更新日期：1999-02-01 00:00:00

abstract：:Adult rat chromaffin cells may proliferate or extend neurites when stimulated by nerve growth factor (NGF) but their response is predominantly proliferative, making them a unique model for studying how mitogenic specificity is achieved. We examined contributions of the NGF receptors trk and p75 and of the major NGF si...

journal_title：Cell and tissue research

authors： Powers JF,Shahsavari M,Tsokas P,Tischler AS

更新日期：1999-01-01 00:00:00

abstract：:The brood pouch of the male pipefish (Syngnathus schlegeli) is a ventral organ located on the tail, with the anterior region closely associated with the genital pore. The embryos in the pouch are attached to highly vascularized placenta-like tissue which seals the pouch folds from inside during incubation. The epithel...

journal_title：Cell and tissue research

authors： Watanabe S,Kaneko T,Watanabe Y

更新日期：1999-01-01 00:00:00

abstract：:Elevated target-derived smooth muscle nerve growth factor (NGF) and resultant neurogenic plasticity are associated with both hypertension and hyperactive voiding in spontaneously hypertensive rats (SHRs: hypertensive, behaviorally hyperactive). In culture, vascular (VSMCs) and bladder (BSMCs) smooth muscle cells deriv...

journal_title：Cell and tissue research

authors： Clemow DB,Tuttle JB

更新日期：1998-12-01 00:00:00

abstract：:Mytilus mussels are characterized by annually repeated reproduction which is associated with subsequent growth, morphogenesis, breakdown and redevelopment of the gonad and reproductive tract into mantle mesenchyme. We present a description of the expression of the male-associated polypeptide (MAP; see Mikhailov et al....

journal_title：Cell and tissue research

authors： Torrado M,Mikhailov AT

更新日期：1998-12-01 00:00:00